Disabled But Able
Patricia Chase is a pretty independent person, but she takes Lucy and Fred with her wherever she goes.
Download the full text of the Request for Applications in PDF format
Apply! for Stroke Recovery Research COBRE Pilot Project funding via SC Clinical and Translational Research Institute
RFA Release Date: Monday, June 3, 2019
Letter of Intent Due Date: Monday, June 17, 2019, 5:00 pm
Application Due Date: Monday, July 15, 2019, 5:00 pm
Earliest Anticipated Funding Date: December 1, 2019
COBRE in Stroke Recovery’s Pilot Program aims to attract additional junior and senior investigators into the field of stroke recovery research, promote utilization of the scientific cores, develop new collaborations and mentoring relationships, and stimulate new programmatic activities to build long-term sustainability for the Center.
The COBRE in Stroke Recovery Pilot Project Program includes various types of awards, modeled on SCTR’s categories, as shown below.
Brief Description: Generate critical preliminary data for a planned submission/resubmission of an extramural grant application within 6 months.
Award Amount: Up to $10,000
Award Duration: Up to 1 year
Brief Description: Provide mentored research experiences for junior investigators who will use the cores and may become candidates to replace current COBRE Junior Investigators as the graduate.
Award Amount: Up to $30,000
Award Duration: Up to 1 year
Brief Description: Provide strategic support to explore the feasibility of projects that might become collaborative R01s or center grants.
Award Amount: Up to $30,000
Award Duration: Up to 1 year
Brief Description: Provide support for new equipment or techniques to ensure that core capabilities continue to be current and innovative.
Award Amount: Up to $50,000
Award Duration: Up to 1 year
Access the application submission portal at:
Dr. Narendra Banik
The main objective of the program is to promote the growth of the COBRE in Stroke Recovery through the development of new extramural funding and the utilization, enhancement and advancement of critical technologies and COBRE in Stroke Recovery core services. The pilot project program is not designed to provide ongoing support for a long-term project or to provide supplemental support to ongoing funded research projects.
Pilot Projects Must Aim To:
Pilot project grants will support four general categories of pilot projects associated with COBRE in Stroke Recovery: Fast Forward Pilot Grants, Mentored Investigator Pilot Grants and new translationally-based Discovery Pilot Grants. They will not be used to provide ongoing support for a project or provide bridge funding. Indirect costs (F&A) will not follow pilot project subawards; pilot project budgets will fund direct costs only. Funds may be requested for standard allowable expense categories such as key personnel and technical support (including fringe benefits at institutionally established rates), research supplies, professional travel directly beneficial to the proposed research, and other direct costs such as laboratory animal costs, research subject compensation, and data analysis/statistical support. Pilot project funds may not be used for general purpose equipment (e.g., computers), supplies, administrative support, publication costs, subscriptions or memberships. No pilot project funds may be used for renovations or alterations.
will be available to research faculty members who can generate preliminary data for a planned submission/resubmission of an extramural grant within 6 months. Multiple Principal Investigators (MPIs) are permitted if/as consistent with the planned extramural submission. Special consideration will be given to applications supporting resubmissions that generate new data in response to prior review. Investigators will be required to submit their summary statement for evaluation of responsiveness of proposed work to reviewers’ comments.
will be available to research faculty members who qualify as an NIH New Investigator (he/she has not previously competed successfully as PD/PI for a substantial NIH independent research award or its equivalent) who wish to develop an independent program of research that complements the focus of COBRE in Stroke Recovery. Applications in this category must include a Pilot Project Mentor who will provide a detailed letter of commitment describing the mentoring arrangements (e.g., frequency of meetings, access to space and/or equipment) and focal areas (knowledge, techniques or skills) critical to the project’s outcome and the pilot investigator’s research career development. The Mentored Investigator must be named as the PI of the pilot project; MPIs are not allowed in this category. Mentored Investigator Pilot Grants may request funds for protected time for the Investigator to conduct the proposed research, technical support (postdoctoral stipend, research assistant salary), research supplies, statistical support, animal models (purchase, per diem costs), research subject compensation and transportation, and/or other allowable direct costs of conducting the proposed study.
will be available to faculty members of any rank whose proposal is translationally-based and directly relevant to the COBRE in Stroke Recovery theme. Proposals in this category must include a compelling rationale that clearly establishes direct relevance to the COBRE in Stroke Recovery mission and objectives in stroke recovery, the Principal Investigator’s qualifications to undertake this line of investigation, and a viable plan for obtaining competitive extramural grant funding. MPIs are permitted if/as consistent with planning for future extramural submission(s). Discovery Pilot Grants may request funds for an appropriate level of effort for the PI/Project Director, collaborator(s) and/or co-investigator(s), technical support, research supplies, and other allowable direct costs of conducting the proposed study, as described above, with the same constraints for equipment and/or professional travel.
Investigators may submit only one application as PI or MPI in any pilot project category per annual funding cycle. In addition, investigators may serve as Mentor for only one Mentored Investigator Pilot Grant per annual funding cycle. Investigators may serve as co-investigator on multiple applications.
The PI of a pilot project proposal in any category must be a full-time faculty member at the Medical University of South Carolina and must have a doctoral degree. Collaboration with investigators at other institutions is encouraged in roles such as co-investigator, consultant, collaborator, advisory member, mentor or co-mentor, as appropriate. Individuals who are not US citizens or permanent residents are eligible to apply as PI if the terms and conditions of their faculty appointment and commitments are conducive to successful completion of the pilot project grant and support the probability of sustaining the COBRE center’s growth and development through future extramural research funding and/or core resource enhancements.
Applicants for Mentored Investigator Pilot Grants may not have been or currently be PI of an NIH R01, P01 sub-project or equivalent. Mentored Investigator PIs must designate a primary research mentor for the pilot project, who may be from inside or outside MUSC. The mentor must have recognition as an accomplished scientist in his/her chosen field, a strong history of competitive research support, and a track record of success in training independent investigators.
Applicants for Discovery Pilot Grants may be faculty of any rank at MUSC and should have a record of accomplishment in their chosen field.
Previous recipients of a Mentored Investigator Pilot Grant would not be eligible to compete again for additional funding in that category. However, a Mentored Investigator grantee or a Discovery grantee could conceivably apply for a future Discovery grant.
Applicants with current IDeA (e.g., COBRE or CTR) or INBRE funding are not eligible for funding under this opportunity.
Although a Letter of Intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows us to estimate the potential review workload and plan the review. Prospective applicants are asked to submit a Letter of Intent that includes the following information:
The Letter of Intent should be submitted by email to the COBRE in Stroke Recovery Pilot Project Program office LuAnne O’Connor (email@example.com) by 5:00 p.m. on June 17, 2019.
Applicants will have the opportunity to submit one revised application in response to review comments from a previous COBRE in Stroke Recovery Pilot Project Program application. Revised applications should be submitted during the following COBRE in Stroke Recovery RFA cycle. Investigators submitting a revised application will be expected to address the review critiques using the NIH-modeled Introduction to Resubmission Application, limited to 1 page. The Introduction must summarize all substantial additions, deletions and changes to the application. The Introduction also must include a response to the issues and criticism raised in the Summary Statement. Revisions must be highlighted throughout the revised application to facilitate the re-review process. Substantial scientific changes must be marked in the text of the application by bracketing, indenting or changing typography. Do not underline or shade the changes. Deleted sections should be described but not marked as deletions. If the changes are so extensive that essentially all of the text would be marked, explain this in the Introduction. Additional guidance can be found in section 2.7 “Resubmission” Applications, of the NIH Application Guide SF424 (http://grants.nih.gov/grants/funding/424/index.htm).
Applicants should submit the application materials through the SCTR website by clicking the appropriate “Apply” link (http://academicdepartments.musc.edu/sctr/programs/pilot_projects). All applications consist of an online form and four PDF uploads.
Online Form (Entries with an * are required fields)
PDF Upload 2: Project Description and Relevance
PDF Upload 3: Research Plan
PDF Upload 4: Budget and Justification
Each application will be assigned to at least two reviewers with appropriate expertise and without conflict of interest, who are faculty members at MUSC or outside academic institutions. Statistical reviews will also be conducted on each application as appropriate. Reviewers are instructed to evaluate the quality of the research (significance, investigator(s), innovation, approach, environment) using the 9-point NIH rating scale (1=Exceptional to 9=Poor). The reviewers will address the ‘Additional Review Considerations’ listed below for each application as applicable, and will generate an Overall Impact Score based on the quality of the research and the ‘Additional Review Considerations.’ An NIH-style study section meeting will be held to discuss reviews and prioritize the applications based on the overall impact score, Summary Statement, and the programmatic needs of the COBRE in Stroke Recovery. Funding recommendations will be forwarded to the COBRE in Stroke Recovery External Advisory Committee for final funding decisions. Applications selected for funding by the COBRE in Stroke Recovery Executive Committee and External Advisory Committee will then be submitted to NIH for final approval. Applicants are strongly urged to begin the process of obtaining required IRB, IBC, and IACUC approvals associated with project as soon as possible, as final approval from NIH to begin the project cannot be provided until all approvals are in place. Investigators needing assistance should submit a request through SCTR SPARC Services Catalog (https://sparc.musc.edu/).
Each publication, press release, or other document about research supported by the Stroke COBRE Pilot Project Program must include an acknowledgment of NIH award support and a disclaimer such as “Research reported in this publication was supported by the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number P20GM109040. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”
In addition, the PI should also add the SCTR grant acknowledgment information if they receives any
form of SCTR support, consults etc. Please see the weblink below.
Additional Review Considerations for ALL Grant Categories
Additional Review Considerations for Mentored Investigator Pilot Grants
Additional Review Considerations for Discovery Pilot Grants