Clinical & Translational Tools & Resources Core Capabilities

Participant move dried beans into bowl during motor skill testing

The Clinical and Translational Tools and Resources (CTTR) Core leverages CTSA infrastructure in research coordination and recruitment, biomedical informatics and biostatistics. CTTR’s recruitment efforts partner with the SCTR Biomedical Informatics group to maintain and enhance a new Registry for Stroke Recovery (RESTORE) incorporating CTSA best practices and informatics standards. CTTR also leverages the outstanding expertise with applications to neuroscience in the Division of Biostatistics and Epidemiology at MUSC.

CTTR Resources

RESTORE provides a powerful new research tool, integrating data from multiple sources for targeted queries. The data from all of the individual projects will be aggregated and synthesized into a whole that will be greater than the sum of its parts. For feasibility studies, it gives investigators the power to determine realistic sample sizes and availability of data/specimens in the project design phase. After project initiation, this tool accelerates data analysis and expands breadth of data available through the combination of demographics, clinical measures, quantitative data, treatment outcomes, and genetic data (when available) into a single readily queried database. Furthermore, links to the complete data sets (including time series) from the science cores (e.g., neuromechanical data from behavioral measurements such as gait analyses, neurophysiological data from TMS protocols, and neuroimaging data from structural or functional MRI scans) allows highly innovative follow-up studies as new analyses are developed by the science cores and as new multidisciplinary concepts are generated through integrating the comprehensive data set.