Agenda and Speakers for Clinical Trials Workshop

Design & Analysis of Clinical Trials in Neuromodulation

Monday, April 27, 2020

9:00 AM

Welcome and Introduction

Steve Kautz, PhD and Marcas Bamman, PhD

9:10 AM

Keynote Address

Mark George, MD

9:50 AM

Q and A

10:00 AM

Designing Neuromodulation Trials UAB

Pilots/small studies

Phase I, II trials - Dose finding trial nuances

Phase III trials

Gary Cutter, ScD and Marcas Bamman, PhD

10:45 AM

Q and A

11;00 AM

Two-site combinatorial therapy trial planned by MUSC and UAB which combines rTMS and aerobic exercise rehab post-stroke.
Nuances and challenges of designing and conducting a randomized trial involving more than 1 intervention in combination

Chris Gregory, PT, PhD; Mark George, MD; Marcas Bamman, PhD; Gary Cutter, ScD

11:40 AM

Q and A

11:55 AM

Lunch Break

12:30 PM

Statistical Analyses for longitudinal studies MUSC

Linear Mixed Models

Multilevel Models

Generalized Linear Mixed Models

Data Reduction

Viswanathan Ramakrishnan, PhD

1:15 PM

Q and A

1:30 AM

Case study 1 - MUSC
Interactive session and Q and A

Viswanathan Ramakrishnan, PhD and Lisa McTeague, PhD

2:30 PM

Case study 2 - UF/MUSC
Interactive session and Q and A

David Clark, PhD; Marcas Bamman, PhD; Viswanathan Ramakrishnan, PhD; Steve Kautz, PhD

3:30 PM

Concluding remarks

Steve Kautz, PhD and Marcas Bamman, PhD